Homeopathy is a 200 year old Medical discipline with a proven track record of both safety and efficacy. Due to the foundational principles of using natural substances in an infinitesimal dose within a diagnostic method of “like curing like”, there are no known contraindications to pharmaceutical drugs. Homeopathic preparations have been regulated under the law since the inception of the Food, Drug and Cosmetic Act, authored by Senator Royal Copeland, M.D., a practicing homeopath, in 1938. (40)
Homeopathic preparations are recognized as drugs under the Federal Food, Drug, and Cosmetic Act (“FD&C Act”), 21 U.S.C. § 201 et seq. Section 201(g)(1) of the FD&C Act, 21 U.S.C. § 321(g)(1), which defines the term “drug” as “articles recognized in the official United States Pharmacopoeia, official Homeopathic Pharmacopoeia of the United States, or official National Formulary, (i) or any supplement to any of them . . . .” (40)
Slenderiix employs a modernized approach to homeopathy, blending individual proven remedies into one cohesive formula to effectively address all imbalances which contribute to abnormal weight gain. Contributing factors include hormonal responses to excessive stress—whether dietary, emotional or environmental; capacity for cellular detoxification, neurotransmitter communication, stable hunger patterns and freedom from addictive behaviors, all of which contribute to systemic flushing of abnormal fat stores, when balance in achieved. Slenderiix was successfully tested in over 10,000 patients prior to ARIIX obtaining exclusivity and beginning in-house beta testing and clinical observation.
The Materia Medica catalogs all methodology within the discipline of homeopathy and references the functions of each remedy as excerpted below:
- Ammonium Bromatum: Indicated in chronic laryngeal and pharyngeal catarrh, neuralgic headaches, and obesity.
- Avena Sativa: Exhibits selective action on brain and nervous system, favorably influencing their nutritive function. Indicated in nervous exhaustion, sexual debility, and addictive morphine habit call for this remedy in rather material dosage. Best tonic for debility after exhausting diseases and sleeplessness, especially of alcoholics. Also addresses nervous states of many chronic female concerns.
- Calcarea Carbonica: chief action is supporting impaired nutritional metabolism as the key action; the glands, skin, and bones, being most instrumental in changes evidenced. Needed for increased local and general perspiration [for normal systemic detoxification]… nausea, acidity, breathlessness, a jaded state—mental or physical, due to overwork.
- Fucus Vesiculosis: A remedy for obesity and non-toxic goiter, thyroid enlargement in obese patients. Digestion is enhanced, normalizing obstinate constipation, and flatulence diminished.
- Graphites: An anti-psoric carbon, most active in stout individuals with fairer complexions, with tendencies toward skin affections and constipation, excess fat storage with tendency to obesity, chronic low body temperature, with delayed menstrual history, who become cold easily, may suffer anæmia with redness of face, tendency toward inflammation of the pylorus or duodenal illness.
- Ignatia Amara: One of the chief remedies for hysteria. It is especially adapted to the nervous temperament-women of sensitive, easily excited nature, quick to react, rapid in execution and change of mental and physical condition, nervous, apprehensive, rigid, trembling who suffer acutely with mental or physical stress.
- Lycopodium Clavatum: supports conditions where ailments are gradually developing with functional weakening regarding, digestion, liver function, predisposition to uric acid metabolism, intolerance to cold, and muscular strength. Marked regulating influence upon the glandular (sebaceous) secretions, those benefitting from Lycopodium lack vital heat [indicating optimal metabolism] have poor circulation, with cold extremities, acute temporary pains, and sensitive to noise and odors.
- Nux Vomica: Typical individuals calmed by Nux are thin, spare, quick, active, nervous, and irritable. Especially adapted to digestive disturbances, flatulent abdominal distention and hypochondrial states, Nux may also address conditions such as ravenous hunger, sour taste in mouth, nausea in the morning after eating; weight and pain in stomach, and feeling worse after eating.
- Sulfuricum Acidum: This remedy supports those with chronic acidosis, digestive tract abnormalities, and may be evidenced by a craving for stimulants. Tremor and weakness; hurried temperament, hot flashes followed by perspiration, with trembling, rate of healing after medical procedures, gastralgia and hypochlorrhydria.
- Thyroidinum: Exercises a general regulating influence over the mechanism of the organs of nutrition, growth and development. Used in psoriasis, tachycardia, arrested development in children, linked to improvement in memory, goiter, obesity, mammary tumors, uterine fibroids, fibroid tumors of the breast. Addresses the sensation of faintness and nausea, extreme weakness and hunger, sensitivity to cold and symptoms of Hypothyroidism after acute diseases, i.e, weakness, easy fatigue, weak pulse.(41)
i. Since the passage of the FD&C Act, the United States Pharmacopoeia and the National Formulary have merged.
ii. As noted, with the merger of the United States Pharmacopoeia and the National Formulary there are only two “official” compendia.
iii. Homeopathic drugs are also covered by the Medicare-Medicaid Statute, 42 U.S.C. § 1395x(t), which defines drugs to “include only such drugs . . . as are included (or approved for inclusion) in the United States Pharmacopoeia, the National Formulary or the United States Homeopathic Pharmacopoeia.”
Xceler8 Metabolism and Energy Support is a patented blend of methylcobalamin, biotin, and a synergistic blend of a specific classification of herbs known as adaptogens, due to their proven ability to improve resilience to stress, increase adaptive responses and to reduce the perception of stress. (42)
The coenzyme form of B12, known as methylcobalamin, provides the foundational structure of the Xceler8 product. This methyl donating form of B12 is superior to analog chemical copies of B12 that are typically used in pharmaceutical drugs, inexpensive vitamins and processed foods. (43) Various methyl donors are required in the body for chemically transforming substances into usable forms for fuel, as well as for neutralizing destructive byproducts such as homocysteine into benign substances, which would otherwise contribute to disease. Methylcobalamin is the only form of B12 that is able to dispose of homocysteine through methylation and enables the production of SAMe, S-adenosyl methionine), the most important methyl donor for adequate glutathione levels (i.e. optimal metabolism and immune function) to be possible. (44)
Cyanocobalamin, is chemically derived vitamin B cleaved to a cyanide molecule, which requires a methyl donor to be broken down by the liver to split off the (toxic) cyanide component, allowing the remainder to be converted to the biologically active form of methyl B12. This synthetic cyanocobalamin B12 is typically 100 times cheaper than methylcobalamin, and contributes to system-wide methyl donor depletion, which can cause a relative shift in homocysteine metabolism, increasing significant risk of heart disease, neurological degeneration and measureable age-related brain shrinkage.
“Homocysteine tends to accumulate in the body whenever B12 gets deficient, and this accumulation has been linked with increased risk of cardiovascular disease, chronic fatigue syndrome/fibromyalgia and multiple sclerosis, and Alzheimer’s Dementia, among other conditions.” (44)
An Oxford University study, published in The Journal of Neurology, reported an estimated 40% of the population is deficient in B12. (45) B12 deficiency is so wide spread because of commonly used pharmaceutical drugs like estrogen containing birth control pills, antacids, including excessive calcium supplementation; antibiotics, anti-cancer drugs, anti-psychotics, and anti-diabetic medications all directly cause B12 depletion. Without adequate B vitamins to suspend the bile salts in the liver, fat soluble nutrients are not able to be assimilated, resulting in compromised metabolic, neurological and immune function.
Subjects in a study reported in Neuropsychopharmacology comparing the effects of methylcobalamin as compared to cyanocobalamin, reported remarkable results in only one week of supplementation. Methyl B12 users reported reduced sleep time, with increased sleep quality and feeling more well-rested upon rising, increased day time energy and ability to concentrate. (46) Restoring appropriate levels of B12 supports healthy energy levels and excellent neurological performance. (43) Biotin is a coenzyme and B vitamin, which, when combined with chromium, has been shown to reverse insulin resistance and support health blood sugar levels. Even when tested in isolation, biotin plays a significant role in several key metabolic functions in digestion, the skin and nervous systems, supporting repair of nerve pathology due to type 2 diabetes, and improved glycemic control. (47)
Rhodiola Rosea and Ashwaganda are adaptogenic herbs used traditionally in Chinese Medicine and Ayurvedic Medicine, and are defined by their ability to have a normalizing effect on the body, allowing the individual to become more resilient to chronic stressors, whether physical or emotional. Adaptogens are non-toxic plant based therapies that normalize physiological functions which have been disturbed by chronic stress, and work through correction of balance to the neuroendocrine and immune systems. (42) Adaptogens have been used successfully to treat a milieu of chronic health conditions for over 100 years, contributing to current theory that stress is the number one contributor that drives pathology of all diseases. Specifically, rhodiola has been shown to prevent the excess release of cortisol and adrenaline in response to stress, also blunting the increase in cholesterol and triglycerides typically triggered in response to stress. It helps to transport serotonin precursors, reducing depression, and increases body fat to muscle ratio by mobilizing fatty acid stores during exercise, allowing increased fat burning. (42) Ashwaganda has been used successfully in both India and China as an aphrodisiac, to treat insomnia, anxiety, fibromyalgia and arthritis, and used to promote emotional balance in cases of depression and mental or physical fatigue. (42)
Vitamins and Minerals
ARIIX’s Vitamin and Mineral, known as “Optimals” contain a signature whole food dried vegetable juice blend that is certified to be grown from GMO free seeds and without pesticides. This blend includes broccoli, carrot, tomato, beet, spinach, cucumber, Brussels sprout, cabbage, celery, kale, asparagus, green bell pepper, cauliflower, parsley, and wheat grass. The vegetable blend adds important enzymes, peptides, and phytonutrients that support the body’s ability to absorb and utilize vitamins and minerals, and to help offset the diets of those who have low daily consumption of vegetables. Rice bran contributes naturally whole complex antioxidants, magnesium, calcium, Vitamin A carotenoids, and nine B vitamins, along with several essential amino acids and phospholipids, which are necessary for maintaining healthy cell membranes.
Every ingredient in the Optimals is certified as of non-GMO origin and these products are manufactured in an OTC facility and certified for efficacy, purity and potency by NSF, GMP and the FDA, providing exacting standards of quality assurance, dependability of consistency and purity.
Studies have concluded that supplements containing natural food nutrient complexes are better than supplements containing only isolates. 
Getting appropriate levels of vitamins and minerals every day is essential to not only a high functioning metabolism, but these can be the critical differentiators between vital health and the simple absence of an illness. Because most people in the world are deficient in one or more of the 40 vitamins, minerals and other essential biochemical nutrients necessary every day for minimal survival, and the human body was created with an innate ability to adapt to amazing variables and still survive, we observe most people today experience life, not in a state of vital health, but fluctuating on the continuum between the absence of illness and experiencing illness.
Most individuals are grossly deficient in the critical “Metabolic Supportive Nutrients”, which are crucial to appropriate blood sugar control, stress responses, methylation of foods into usable forms that can actually nourish the body, and controlling every enzyme reaction from fluid regulation to neurotransmitter production. As a nation, Americans are over fed and yet, undernourished and chronically stressed. This chronic state of deficiency results in a down shifting of the metabolism to attempt to spare what nutrient resources are remaining. This is most evidenced by mental sluggishness, poor digestion, daytime fatigue, poor sleep, chronic aches and pain due to inflammation, and cravings that are not satisfied by food. As the brain signals the body to input more nutrients to try to satisfy these vital deficiencies, and people answer these signals with low-nutrient convenience foods notoriously high in sugar, starch, vegetable oils, chemical additives and stimulants; metabolism continues to down regulate and disease breeds at a faster rate.
Bruce Ames, Ph.D., professor of biochemistry and molecular biology at the University of California, Berkeley, analyzed over a hundred diseases that are triggered by nutrient deficiencies. These symptoms in the early stages are typically identified by traditional medicine as “typical signs of aging”, but with obesity and other metabolic, chronic inflammatory and autoimmune diseases becoming more common in adolescence and children, his revolutionary analysis, “The Triage Theory ”(1, 2) has not come too soon. In his observations, he found that over 50 enzymes within the body are completely dependent upon daily intake of adequate amounts of vitamins, minerals and essential fatty acids in order to be catalyzed. Without consistent adequate levels of these three complexes every day, it is impossible for the body’s enzymes to begin their work and for humans to experience vital health and optimal metabolism.
These nutrients, which have to be taken in daily, a minimum of twice a day, to replenish fuel necessary for routine cellular renewal throughout the day, are the critical factors which determine whether human genes are prompted to express health or disease. Dr. Ames found that a deficiency of any 1 of this array of critical micronutrients, posed a threat of oxidative stress damage to cellular integrity and metabolism that was equal to and in some circumstances, greater than 100 times the known damaging effects of radiation! (1,2,3,6) It is established that if individual cells within the organs of the body have a low metabolism due to low fuel levels, then these organs will also be functioning at a lower than optimal level, which means the entire body is then operating in survival mode of a low functioning metabolism, while usually experiencing a default of fat storage to conserve nutrient resources, and creeping closer to disease.
Continuing his work at the Nutrition and Metabolism Center, Children’s Hospital and Research Institute, Oakland, CA; Dr. Ames observes what he describes as a shift within the body toward short-term survival gene expression as a coping mechanism in times of low nutrient intake. This shifting into survival mode simultaneously requires sacrificing expression of genes that produce long-term health. (4) This means that if we see individuals whose bodies are downshifting and accommodating to low nutrient intake by storing fat abnormally to spare nutrient reserves; this single indicator—belly fat, is enough to indicate life-shortening inflammatory diseases are not far down the timeline if these nutritional deficiencies are not quickly remediated with therapeutic dosing of these essential nutrients. (5,6) Dr. Ames also postulates that micronutrient deficiencies that trigger the triage response would accelerate cancer, aging, and neurological decline, but would leave critical functions like ATP production, intact.(7)
The National Health and Nutrition Examination Surveys (NHANES) has long reported that the food intake of the following groups of people in the United States does not provide adequate nutrition from all 40 essential nutrients for adequate health: the poor, teenagers, menstruating women, the obese, and the elderly; but they are now reporting according the Estimated Average Requirement (EAR), that micronutrient levels from food are probably not adequate for anyone else either, to express optimal health without disease. (7)
Westernized diets are typically characterized by excessive calories from starchy carbohydrates and processed oils, and below micronutrient thresholds determined essential for minimal health. Dr. Ames notes that this low consumption of micronutrients accompanied by calorie excess may be the norm with those that are overweight and obese, and contributes to the deadly diseases associated with obesity. “Significant chronic disruption may occur when consumption of micronutrients is below the current RDA (8) but above the level that causes acute symptoms. When one component of the metabolic network is inadequate, there may be a variety of repercussions in metabolism, including acceleration of degenerative diseases.”(7)
Due to these findings, a high-quality multi-vitamin is recommended as a low-cost preventative intervention in combination with the healthiest possible food choices. This is the best low cost adjunctive for optimal health and reducing the risk of common age-related diseases associated with obesity, and ultimately death by secondary diseases of CHD and cancer.
Recognized authorities in Nutritional Medicine such as Ray Strand, M.D., Julian Whitaker, M.D., Jane Higdon, Ph.D., Michael Murray, N.D., Phyllis Balch, CNC, Nicholas Perricone, M.D. and six other known figures practicing proactive preventative nutritional medicine, were consulted to create what became known as the Blended Nutritional Standard. (9) This was constructed by employing 18 criteria across 48 ingredients based upon their independent input for optimal therapeutic nutrient recommendations. This Blended Standard has become the bar that therapeutic quality multi-vitamins are measured against to determine if they are prepared in adequate dosing of non-toxic and effective forms of each nutrient, and if all essential nutrients are present and combined in the correct ratios one to another. The Optimals adhere to this Blended Standard.
Dr. Ray Strand, in his book Healthy for Life, notes that these nutrients are needed in greater amounts than can usually be obtained by food alone. In his practice, he has personally seen reversal of Type 2 Diabetes in hundreds of patients who optimize their nutrient intake with critical levels of vitamins, minerals and essential fatty acids and who employ the lifestyle modifications described in his Healthy for Life program. He also testifies to incredible gains in glycemic control with Type 1 Diabetics, and reversing the symptoms of metabolic syndrome, thereby preventing the onset of Diabetes in thousands of people worldwide using a similar combination of appropriate supplementation, low-glycemic diet and modest exercise. (10)
Omega 3 Fatty Acids
It is now generally maintained that inflammation is the root cause of the chronic degenerative conditions. Systemic inflammation is indicated by abnormal fat storage, swelling, chronic joint and bone pain, allergies, asthma, and headaches in the early stages; but also heart disease and cancer and neurological diseases, as these earlier symptoms continue unchecked.
Anti-inflammatory omega 3 fats in bio-available fish oil lower the production of prostaglandins and cytokines that trigger inflammatory responses. Clinical studies have shown that stress and depression are associated with too many inflammatory cytokines in the body, and not enough anti-inflammatory omega 3 fats are one of the foremost contributors. These two factors typically are present before abnormal fat storage begins, and continue to mount along with unwanted weight. When weight is concentrated in the stomach area, this visceral adipose tissue begins to generate more inflammatory hormone signals, rapidly elevating whole body inflammation, and driving the disease process to escalate, which also locks up fat stores making them unavailable for fat burning, even in times of a calorie deficit. (3)
Although the American Heart Association (AHA) suggests if triglycerides are high (200 mg/dL or higher)(1,2), taking 2,000-4,000 mg of fish oil with EPA and DHA along with dietary changes is an effective way to reduce risk factors within a 90 day period, most integrative medicine specialists initially use a therapeutic loading dose with a minimum dose of 4000 mgs of omega 3 oils per day, Those who are severely obese, depressed, or stressed may use much higher doses to get significant results within a 90 day time frame.(4)
Because of the state of the environment today, many fish contain high levels of mercury, PCBs (polychlorinated biphenyls), dioxins and other environmental toxins, which concentrate in fat stores of both the fish and the people who consume them and their oils. These fat-soluble toxins lock up fat cells and contribute to the metabolic dysfunction of not being able to lose weight, even when eating less and exercising more.
Many commonly available brands of fish oil supplements are “purified” with hexane, which is a petroleum derivative. Governing officials allow hexane residues to be present as a tradeoff for the removal of the heavy metal residues common to commercially available fish oils. This residual hexane in most fish oil supplements can accumulate over time and cause considerable nervous system damage. (14) Chemicals that are petroleum derivatives, in general are suspected to cause endocrine disruption which can lead to hormone related cancers over time, although this link has not been confirmed through clinical studies pertaining to hexane used for removing heavy metals from fish oils.
ARIIX has sourced a pristine omega 3 fish oil for from the only manufacturer in the world who has patented a unique low temperature, enzyme fermentation purification process which ensures the delicate anti-inflammatory properties are not only kept fully intact, but yields a superior product that is tasteless and odorless, with no unpleasant digestive after-effects that are typical of hexane-distilled or rancid fish oil products common to the shelves of vitamin chains and superstores. Enzyme purification also eliminates chemical waste byproducts, thereby reducing environmental impact resulting from disposing of hexane into the environment.
Restoriix — Detoxification
ARIIX Restoriix is a blend of zeolite, chia seeds and nutrient-dense organic spirulina, chlorella and chlorophyll. Zeolites are highly alkaline minerals that contain large structural vacancies and a negative ionic charge, giving them superior binding adhesion to negatively charged pathogenic toxins. The zeolite blend sourced for Restoriix is ultra-purified and certified free of lead and other contaminants, common to earth-sourced minerals. The highest grade nano-sized particles provide for increased surface area adhesion of free radicals and environmental pathogens, as well as smooth palatable texture. The honeycomb-like molecular structure attract impurities within vacancies, preventing the resorption of toxins as they excreted from the body.
Chia seeds are a superior source of vegan protein and contain over 30 nutrients. Rich in omega 3 fatty acids, containing more than three times the antioxidant capacity of blueberries and 35% fiber by weight, chia seeds detoxify the digestive tract while providing nutrients which rebalance omega 3 to 6 ratios. Insoluble fiber scrubs intestinal walls and loosens impacted debris and the balance of soluble fiber effectively absorbs up to twelve times its weight in fluids. (36)
Chlorophyll-rich plant foods such as chlorella and spirulina are dense in RNA proteins which repair damaged DNA. Excessive toxic load causes over production of free radicals and this mutates DNA, causing premature aging and accelerating disease pathology. Aging and disease are observed when DNA mutations occur within the cells and these damaged cells reproduce. Since chlorophyll is the highest known food source of RNA repair proteins, finding foods sources rich in chlorophyll would inhibit DNA mutations from reproducing, according to Dr. Benjamin Frank’s work in RNA diet therapy. Dr. Frank pioneered dietary nucleic acid therapy which has proven RNA and DNA rich supplements reverse symptoms of aging and disease and increase metabolism by increasing cellular energy (ATP) for improving intercellular communication in the body, for improved rejuvenation, detoxification, and rapid healing. (35)
Marine biologists were first to observe the anti-aging effects of these green sea vegetables on mammals. Ocean mammals consuming large amounts of chlorophyll-rich sea vegetables, including spirulina and chlorella, have no visible signs of aging once they reach adolescence. Chlorella has more than twice the RNA density per gram of any animal protein, making it the richest dietary source of these detoxifying nutrients.
Spirulina is high in natural iodine, which nourishes the thyroid, protects all glandular tissues and ultimately supports both immune and metabolic function. To improve metabolism, spirulina has been proven to improve glycemic control and dislipidemia in Type II diabetics. (38) High in metallo-thionine compounds, Spirulina has been shown to shield the body from radioactive isotopes by binding to them, making digestive elimination possible. Spirulina’s chemo-protective effect has shown potential for use in fighting cancer, as well as detoxifying the kidneys from overuse of antibiotics and analgesics. (37) In Russia a study was conducted on 270 children living in highly radioactive areas, and all showed elevated IgE serum levels. This immune system inflammatory response is typically high in due to allergic reactions, but was completely normalized in 6 weeks of feeding spirulina twice daily.(38) In addition, spirulina’s dense array of phytonutrients phytocyanin, chlorophyll and carotenoids contribute to the anti-inflammatory properties which nourish as they purify the body.
With an average alkalinity factor of 9.7ph, negatively charged zeolite minerals bind unwanted toxins and reduce acid ph load at the same time. In addition, when fat is released due to dieting, these toxic stores are freed up to circulate within the body, and can cause significant side effects if they are not completely eliminated by the digestive tract. If toxic load overwhelms these pathways, the possibility of reabsorbing toxins can trigger a protective response of shuttling toxins into fat storage, represented by weight loss plateau or rebound weight gain. Detoxification has been shown to effectively protect against these metabolic set-backs.
Rejuveniix is an energy-boosting blend of low-temperature dehydrated fruit and berry extracts, chosen for their wide variety of polyphenols and bioflavanoids, combined with green coffee bean extract, hawthorne berries and the amino acid l-theanine, for increased mental clarity, stamina and focus. This unique extraction process leaves exceptionally high levels of the beneficial antioxidant levels intact, while producing a product that contains no fructose.
Rejuveniix also contains a blend acai, maqui, sea buckthorn and goji berries, as well as mangosteen and noni fruits. This variety of berries and fruits represents a wide range of antioxidant coverage shown to support immune function, heart health and metabolic sufficiency. Represented within Rejuveniix are anthocyanins, xanthones, a variety of carotenoids such as beta carotene and zeaxanthin, and plant sterols known to support heart health, detoxification and modulate oxidative stress.
2010 findings in the British Journal of Nutrition reported therapeutic effects of berries in modulating postprandial glucose response when eaten with high glycemic foods. After consuming a meal with berries, serum levels were drawn at 15, 30 and 150 minutes, and compared to blood glucose responses at the same intervals following a control meal. The results showed that consuming berries along with sucrose had a significant impact on reducing the digestion/absorption of the sucrose as evidenced by decreased serum postprandial glucose. High levels of polyphenol antioxidants in berries are attributed for this compensory affect. (28)
The focus and energy portion of the Rejuveniix formula comes from a balance of the amino acid l-theanine, hawthorne berries and green coffee bean extract.
L-theanine is sourced from green tea leaves and directly stimulates the production of alpha brain waves, allowing mental alertness (29) and also increases dopamine, “the satisfaction neurotransmitter” allowing individuals to experience a greater sense of pleasure and fulfillment. (30)
Green coffee bean extract is a rich source of chlorogenic acid, which has been shown to have significant effects on both body mass and reducing body fat when used long term in both overweight and obese subjects. (31) Green coffee bean extract has also been shown to suppress hepatic production of triglycerides, reducing fat accumulation. (32) GCBE also works synergistically with kava kava and l-theanine, enhancing effectiveness. In comparison, common sources of caffeine contain cafestol and other compounds associated with the negative effects of using caffeine as a stimulant. Research has shown the combination of ingredients in Rejuveniix to support clarity of mind, positive mental outlook by supporting neurotransmitter production and cellular communication, and healthy energy levels. (33)